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Servicebio Inc electron microscopy experiment
Lnc-CCNH-8 as a potential predictive marker for immunotherapy response in HCC (A) Morphology of exosomes by electron <t>microscopy.</t> Scale bar: 200 nm. (B) Particle size analysis of exosomes. (C) Exosome marker proteins Alix, CD63, and CD81 were detected using western blot. (D) Expression level of Lnc-CCNH-8 (detected using RT-PCR) in plasma-derived exosomes from HCC patients (n = 79) and healthy individuals (n = 30). ∗∗p < 0.01. (E) Expression level of Lnc-CCNH-8 (detected using RT-PCR) under therapeutic efficacy. PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease. ∗p < 0.05. (F) Schematic diagram: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 via dual mechanisms in hepatocellular carcinoma.
Electron Microscopy Experiment, supplied by Servicebio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/electron+microscopy+experiment/pmc10865404-282-16-19?v=Servicebio+Inc
Average 90 stars, based on 1 article reviews
electron microscopy experiment - by Bioz Stars, 2026-07
90/100 stars

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1) Product Images from "Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 in hepatocellular carcinoma"

Article Title: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 in hepatocellular carcinoma

Journal: Molecular Therapy. Nucleic Acids

doi: 10.1016/j.omtn.2024.102125

Lnc-CCNH-8 as a potential predictive marker for immunotherapy response in HCC (A) Morphology of exosomes by electron microscopy. Scale bar: 200 nm. (B) Particle size analysis of exosomes. (C) Exosome marker proteins Alix, CD63, and CD81 were detected using western blot. (D) Expression level of Lnc-CCNH-8 (detected using RT-PCR) in plasma-derived exosomes from HCC patients (n = 79) and healthy individuals (n = 30). ∗∗p < 0.01. (E) Expression level of Lnc-CCNH-8 (detected using RT-PCR) under therapeutic efficacy. PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease. ∗p < 0.05. (F) Schematic diagram: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 via dual mechanisms in hepatocellular carcinoma.
Figure Legend Snippet: Lnc-CCNH-8 as a potential predictive marker for immunotherapy response in HCC (A) Morphology of exosomes by electron microscopy. Scale bar: 200 nm. (B) Particle size analysis of exosomes. (C) Exosome marker proteins Alix, CD63, and CD81 were detected using western blot. (D) Expression level of Lnc-CCNH-8 (detected using RT-PCR) in plasma-derived exosomes from HCC patients (n = 79) and healthy individuals (n = 30). ∗∗p < 0.01. (E) Expression level of Lnc-CCNH-8 (detected using RT-PCR) under therapeutic efficacy. PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease. ∗p < 0.05. (F) Schematic diagram: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 via dual mechanisms in hepatocellular carcinoma.

Techniques Used: Marker, Electron Microscopy, Particle Size Analysis, Western Blot, Expressing, Reverse Transcription Polymerase Chain Reaction, Clinical Proteomics, Derivative Assay, Drug discovery



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Lnc-CCNH-8 as a potential predictive marker for immunotherapy response in HCC (A) Morphology of exosomes by electron <t>microscopy.</t> Scale bar: 200 nm. (B) Particle size analysis of exosomes. (C) Exosome marker proteins Alix, CD63, and CD81 were detected using western blot. (D) Expression level of Lnc-CCNH-8 (detected using RT-PCR) in plasma-derived exosomes from HCC patients (n = 79) and healthy individuals (n = 30). ∗∗p < 0.01. (E) Expression level of Lnc-CCNH-8 (detected using RT-PCR) under therapeutic efficacy. PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease. ∗p < 0.05. (F) Schematic diagram: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 via dual mechanisms in hepatocellular carcinoma.
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Lnc-CCNH-8 as a potential predictive marker for immunotherapy response in HCC (A) Morphology of exosomes by electron microscopy. Scale bar: 200 nm. (B) Particle size analysis of exosomes. (C) Exosome marker proteins Alix, CD63, and CD81 were detected using western blot. (D) Expression level of Lnc-CCNH-8 (detected using RT-PCR) in plasma-derived exosomes from HCC patients (n = 79) and healthy individuals (n = 30). ∗∗p < 0.01. (E) Expression level of Lnc-CCNH-8 (detected using RT-PCR) under therapeutic efficacy. PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease. ∗p < 0.05. (F) Schematic diagram: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 via dual mechanisms in hepatocellular carcinoma.

Journal: Molecular Therapy. Nucleic Acids

Article Title: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 in hepatocellular carcinoma

doi: 10.1016/j.omtn.2024.102125

Figure Lengend Snippet: Lnc-CCNH-8 as a potential predictive marker for immunotherapy response in HCC (A) Morphology of exosomes by electron microscopy. Scale bar: 200 nm. (B) Particle size analysis of exosomes. (C) Exosome marker proteins Alix, CD63, and CD81 were detected using western blot. (D) Expression level of Lnc-CCNH-8 (detected using RT-PCR) in plasma-derived exosomes from HCC patients (n = 79) and healthy individuals (n = 30). ∗∗p < 0.01. (E) Expression level of Lnc-CCNH-8 (detected using RT-PCR) under therapeutic efficacy. PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease. ∗p < 0.05. (F) Schematic diagram: Lnc-CCNH-8 promotes immune escape by up-regulating PD-L1 via dual mechanisms in hepatocellular carcinoma.

Article Snippet: The exosome was suspended in PBS and divided into two parts; one was used for the electron microscopy experiment (Servicebio) and the other was analyzed for particle size using a particle size analyzer (Malvern Zetasizer Nano-ZS 300).

Techniques: Marker, Electron Microscopy, Particle Size Analysis, Western Blot, Expressing, Reverse Transcription Polymerase Chain Reaction, Clinical Proteomics, Derivative Assay, Drug discovery